<i>Aim</i> - To study whether a simple targeted intervention could reduce unwarranted antibiotic treatment in near‐term and term neonates with suspected, but not confirmed early‐onset sepsis.<p> <p><i>Methods</i> - A quality improvement initiative in three Norwegian neonatal intensive care units. The intervention included an inter‐hospital clinical practice guideline for discontinuing antibiotics ...

<i>Background</i> - Mothers with diabetes are less likely to achieve successful breastfeeding. Antenatal breastmilk expression (ABE) may facilitate earlier breastfeeding, but feasibility of introducing ABE and its acceptance among Scandinavian women have previously not been investigated.<br><br> <i>Methods</i> - This observational trial was conducted between the 1 January 2019 and the 12 March ...

<i>Importance</i> - The neonatal early-onset sepsis (EOS) calculator is a clinical risk stratification tool increasingly used to guide the use of empirical antibiotics for newborns. Evidence on the effectiveness and safety of the EOS calculator is essential to inform clinicians considering implementation.<p> <p><i>Objective</i> - To assess the association between management of neonatal EOS ...

Introduction: Coagulase-negative staphylococci (CoNS) are the most prevalent pathogens in nosocomial infections and may serve as a reservoir of mobile genetic elements such as the staphylococcal cassette chromosome mec (SCCmec) encoding methicillin resistance. Molecular characterization of SCCmec types combined with advanced molecular typing techniques may provide essential information for ...

Objective - To evaluate COVID-19 pandemic preparedness, available resources, and guidelines for neonatal care delivery among neonatal health care providers in low- and middle-income countries (LMICs) across all continents.<p> <p>Study design - Cross-sectional, web-based survey administered between May and June, 2020.<p> <p>Results - Of 189 invited participants in 69 LMICs, we received 145 (77%) ...

<i>Background</i>: The epidemiology of early-onset sepsis (EOS) may change over time. Longitudinal surveillance of causative pathogens, antibiotic susceptibility patterns and antibiotic therapy is important for optimal therapy strategies.<br><br> <i>Objectives</i>: To describe the incidence of culture-confirmed EOS, causative pathogens, antibiotic susceptibility patterns and antibiotic therapy ...

<i>Objectives</i>: Neonatal resuscitation guidelines recommend administering intravenous (IV) adrenaline if bradycardia persists despite adequate ventilation and chest compressions (CC). Rapid IV access is challenging, but little evidence exists for other routes of administration. We compared IV, endotracheal (ET), and intranasal routes for adrenaline administration during resuscitation of asphyxiated ...

BAKGRUNN Barn og ungdom med Downs syndrom har et stort behov for oppfølging i primær- og spesialisthelsetjenesten. <p><br>MATERIALE OG METODE Vi publiserte i juni 2019 et spørreskjema på Norsk Nettverk for Down syndrom sin Facebook-gruppe. Formålet var å undersøke brukererfaringer med helsevesenet blant foreldre til barn og ungdom (0–20 år) med Downs syndrom. <p><br>RESULTATER Vi fikk 174 svar. Mest ...

As neonatal resuscitation critically depends upon lung aeration at birth, knowledge of the progression of this process is required to guide ongoing care. We investigated whether expired CO2 (ECO2) levels indicate the degree of lung aeration immediately after birth in two animal models and in preterm infants. Lambs were delivered by caesarean section and ventilated from birth. In lambs, ECO2 levels ...

<i>Background</i> - The first 1000 days of life, from conception to the second birthday, offer a unique window of opportunity for optimal growth, critical for future health. The primary aim of this study was to analyze growth of children between 12 and 24 months age in Tanzanian children, and to explore possible predictors for growth.<p> <p><i>Methods</i> - Observational, cross-sectional study ...